BENCHMARKING OF AN INTERVENTION AIMING AT THE MICRO-ELIMINATION OF HEPATITIS C IN VULNERABLE POPULATIONS IN PERPIGNAN, FRANCE, TO INFORM SCALE-UP AND ELIMINATION ON THE FRENCH TERRITORY

Benchmarking of an Intervention Aiming at the Micro-Elimination of Hepatitis C in Vulnerable Populations in Perpignan, France, to Inform Scale-Up and Elimination on the French Territory

Benchmarking of an Intervention Aiming at the Micro-Elimination of Hepatitis C in Vulnerable Populations in Perpignan, France, to Inform Scale-Up and Elimination on the French Territory

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Hepatitis C virus (HCV) is an important cause of chronic liver disease.Among at-risk populations, access to care is challenging.The French Ministry of Health has supported a seek-and-treat pilot intervention aiming at micro-elimination in Perpignan, France, to inform scale-up of elimination efforts across the whole territory.

University College Dublin (UCD) led a successful EU funded project, called HepCare, focusing on the micro-elimination of HCV.UCD was contracted to evaluate and benchmark the Perpignan results against results from HepCare.Using mixed-method approaches including qualitative interviews with patients, a focus group with healthcare professionals, and quantitative analyses of the cascade of care kit ethos boro across vape x dovpo against results obtained at other European sites, we analyse the acceptability, reproducibility, replicability, and effectiveness of the Perpignan intervention.

A total of 960 participants were recruited in the Perpignan area.HCV antibody test results were obtained for 928 (96.6%), of which 150 (15.

6%) were antibody-positive.Of the antibody-positive participants, 68 (45.3%) tested positive for HCV-RNA, 141 (94%) were linked to care, and of the HCV-RNA-positive participants, invertatop squeeze bottle 60 (88%) started treatment.

Of those who underwent treatment, 34 (56.7%) completed treatment and achieved a sustained viral response (SVR) at dataset closure, 18 (30%) were still in treatment, 5 (8.3%) defaulted from treatment, and 3 (5%) had a virologic failure or died.

The intervention in Perpignan was acceptable to patients, but had limitations in effectiveness, as shown in comparisons with HepCare results.To engage harder-to-reach cohorts in France, future models of care in the territory should incorporate peer support.

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